- The Thirty Fifth State, Manuscript and Galley, 1609/19601
- Thruston family commonplace book, 1604/19251
- Tyler Family Papers, Group D, 1939/19512
- Virginia Cities Collection, 1663/19803
- Virginia Counties Collection, 1600/2000, bulk 1730/18902
- Virginia Records, 1623/19211
- Virginia Records, 1632/19331
- Von Frieling's Salve collection, 1512/1977, bulk 1900/19322
- W. Jett Lauck papers, 1900/19522
- Wade Hampton Frost papers, 1880/19842
- Washington and Lee University and Regional Virginia History Research Collection, 1609/20161
- William Munford Tuck Papers, 1918/19681
- Women's Volleyball records, 1976/20081