- Historic manuscript collection, 1601/19331
- Historical Maps Collection, 1500/20231
- Jack Sandy Anderson, Compiler, Local History Articles and Genealogy Papers, 1600/2011, bulk 2000/20081
- Lynch Family History, 1600/19401
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Map Collection, 1629/19911
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Mining Industry, 1000/20001
- Morley Jeffers Williams Collection, 1602/19671
- Paul Stevens map collection, 1541/17781
- Raleigh (Ralegh) and Carew family correspondence, 1500/16521
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- Shenandoah County Historical Society Collection, 1147/20001
- The Thirty Fifth State, Manuscript and Galley, 1609/19601
- Thruston family commonplace book, 1604/19251