- Ollen Lawrence Burnette, Jr. papers, 1815/20141
- Papers of the Low Moor Iron Company
1873-19271
- Paul Stevens map collection, 1541/17781
- Raleigh (Ralegh) and Carew family correspondence, 1500/16521
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- Richard J. DeMartino papers, 1910/19651
- Richard Lee Morton papers, 1756/2006, bulk 1930/19691
- Saint Andrew's Society of Washington, D.C. records, 1861/19951
- Samuel H. Yonge papers, 1890/19351
- Shenandoah County Historical Society Collection, 1147/20001
- The Thirty Fifth State, Manuscript and Galley, 1609/19601
- Thruston family commonplace book, 1604/19251
- Tyler Family Papers, Group D, 1939/19511
- Virginia Cities Collection, 1663/19801
- Virginia Counties Collection, 1600/2000, bulk 1730/18901