- A. E. Dick Howard papers, 1928/20171
- Berkeley Family Papers
1536-present1
- European figure engravings, 1535/18491
- Henkel Family Papers
1791-18851
- Henry Rose Carter papers, 1775/19471
- Jan Karon papers, 1918/2018, bulk 1964/20181
- John W. Warner papers, 1967/2009, bulk 1967/20081
- Ollen Lawrence Burnette, Jr. papers, 1815/20141
- Papers of the Low Moor Iron Company
1873-19271
- Richard J. DeMartino papers, 1910/19651
- Von Frieling's Salve collection, 1512/1977, bulk 1900/19322
- W. Jett Lauck papers, 1900/19522
- Wade Hampton Frost papers, 1880/19842