- Ann Little Papers, 1947/19671
- Anne and Alan Morledge Collection, 1946/2005, bulk 1969/19881
- Bell Hospital Records, 1926/19701
- Bozarth Family Papers, 1931/1985, bulk 1931/19621
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- Carlton Casey Papers, 1894/19991
- Cynthia Barlowe Collection, 1902/20011
- Cynthia Barlowe and Raymond Kimbrough Collection, 1909/19661
- Daily Press Williamsburg Related Articles, 1950/19901
- Edward Belvin Collection of Williamsburg and James City County materials, 1874/19871
- Eleanor Calkins Papers, 1915/1961, bulk 1927/19611
- Elizabeth Nunn Papers, 1931/19751
- Elizabeth White Willard Papers, 1951/20081
- Fay Parr Papers, 1920/20021
- Fred Frechette Papers, 1930/2000, bulk 1950/20001