- A. Edwin Kendrew Papers, 1930/19591
- Bell Hospital Records, 1926/19701
- Bozarth Family Papers, 1931/1985, bulk 1931/19621
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- Carlton Casey Papers, 1894/19991
- Christian-Charles Family Photographs, 1923/19521
- Cynthia Barlowe Collection, 1902/20011
- Cynthia Barlowe and Raymond Kimbrough Collection, 1909/19661
- Edward Belvin Collection of Williamsburg and James City County materials, 1874/19871
- Eleanor Calkins Papers, 1915/1961, bulk 1927/19611
- Elizabeth Nunn Papers, 1931/19751
- Fay Parr Papers, 1920/20021
- Fred Frechette Papers, 1930/2000, bulk 1950/20001
- Guy Family Papers, 1900/19881
- Hickory Neck Church records, 1721/20241