- George Wilson and Elizabeth Dent Wilson family photos and memorabilia, 1870/19691
- Jefferson Society records, 1825/20181
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/18651
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/197488
- Quinby, Teackle, and Upshur families of Somerset County, Maryland, and Accomack and Northampton Counties, Virginia Papers, 1713/19771
- Richard B. Lillich papers, 1906/19961
- Richard J. DeMartino papers, 1910/19651
- Virginia Scott Cocke Lyman papers, 1898/2025, bulk 1899/19051
- William F. Long papers, 1906/19671
- William Minor Lile journals, 1882/19321