- Howard W. Smith Papers, 1933/19661
- John Bassett Moore papers, 1894/19661
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/18651
- Laine family papers, 1772/19611
- Lewis M. Dabney III papers on Edmund Wilson; William Faulkner and the Yoknapatawpha; and Crystal Ross and John Dos Passos., 1895/20051
- Madison Friendship Lodge Grand United Order of Odd Fellows collection, 1880/19371
- May family papers, 1870/19451
- Norfolk Poet's Club records, 1896/19831
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/197463
- Quinby, Teackle, and Upshur families of Somerset County, Maryland, and Accomack and Northampton Counties, Virginia Papers, 1713/19771
- Russell Stanger Papers, 1920/20081
- Sir Fitzroy Maclean papers, 1827/19961
- Somerville family papers, 1821/20131
- Stella Pratt scrapbook, 1867/19471
- Stowe grocery store ledgers, 1870/19341