- 201st National Guard Regiment Histories, 1949/19911
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Aquilla Matthews papers, 1925/19841
- Audio Collections, 1950/19801
- Berlin B. Chapman Papers, 1922/19951
- Blackley Family papers, 1830/20201
- Braun-Jung Family papers, 1850/20181
- Carter Lowance Papers, 1860/1993, bulk 1942/19881
- Charles Edward Gary, Jr. Papers, 1870/2000, bulk 1940/19801
- Charleston Gazette Publishing Company Records and Chilton Family Papers, 1884/20181
- Coleman-Wilson Papers, 1775/1989, bulk 1883/19641
- Conan W. Vaughan, Jr., Papers, 1923/19921
- Donovan Bond, Journalism Professor, Personal and Professional Papers, 1861/1998, bulk 1914/19801
- E.C. and H.B. Eagle Papers, 1910/19801
- Edward E. Thompson Papers, 1932/19871