- Alumni Association Records, 1833/2014, bulk 1950/20051
- Amos Koontz Papers II, 1865/19701
- Andrew Edmiston Jr. (1892-1966) Papers, 1916/19481
- Aquilla Matthews papers, 1925/19841
- B. Floyd Flickinger Papers, 1927/19501
- Beverley R. Tucker papers, 1886/19731
- Blackley Family papers, 1830/20201
- Braun-Jung Family papers, 1850/20181
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Captain Jimmie Slosson letters, 1925/19571
- Carter Glass Papers, 1820/19461
- Carter Lowance Papers, 1860/1993, bulk 1942/19881
- Charles Edward Gary, Jr. Papers, 1870/2000, bulk 1940/19801
- Charles McCamic (1874-1956) Papers, 1919/19561
- Charleston Gazette Publishing Company Records and Chilton Family Papers, 1884/20181