- Alexander Haight family collection, 1764/19761
- Alfred E. Bradley Papers, 1864/1922, bulk 1916/19181
- Amos Koontz Papers II, 1865/19701
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Carter Glass Papers, 1820/19461
- Clarence Edwin Smith (1885-1959) Papers, 1787/19572
- Coleman-Wilson Papers, 1775/1989, bulk 1883/19641
- Craft Family Collection,, 1861/19191
- Dayton and Woods Families Genealogies and Correspondence, 1849/19601
- Dr. J.C. Easton, History Professor, Papers, 1860/1960, bulk 1935/19601
- Frances Packette Todd Papers, 1800/19851
- Hall Family Papers, 1810/20071
- Harrison and Doddridge Counties, Papers, 1778/19551
- Heatwole Family Papers, 1838/20011
- John Turner Henley Papers, 1857/1921, bulk 1918/19211