- Alexander Haight family collection, 1764/19761
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Carter Glass Papers, 1820/19461
- Clarence Edwin Smith (1885-1959) Papers, 1787/19572
- Coleman-Wilson Papers, 1775/1989, bulk 1883/19641
- Dayton and Woods Families Genealogies and Correspondence, 1849/19601
- Frances Packette Todd Papers, 1800/19851
- Hall Family Papers, 1810/20071
- Harrison and Doddridge Counties, Papers, 1778/19551
- Heatwole Family Papers, 1838/20011
- John W. Davis, Lawyer, Papers, 1842/19781
- Lewis Family Papers, 1825/19361
- Maxwell Family Papers, 1845/2017, bulk 1845/19501
- Myers-Burrage-Graham papers (I), Group A, 1776/19251
- Offley Family Papers, 1818/19161