- Baytop-Fitzhugh Papers, 1840/18661
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Brown, Coalter, Tucker Papers (II), 1791/19201
- Dr. Henry Wythe Tabb Papers, 1847/19491
- Gregory Family papers, 1829/1920, bulk 1880/19001
- Helen M. Hoskins papers, 1839/1868, bulk 1845/18601
- J. Willcox Brown and Turner Macfarland Letters, 1828/18671
- Lottie V. Clark Papers, 1849/19151
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- McDowell Papers, 1839/18651
- Robb-Bernard Papers, 1665/1980, bulk 1850/19501
- See Family Papers, 1821/19181
- Shipman-Wills Papers, 1833/18701
- Susan Rebecca Buck Poetry Album, 1852/18651
- Tucker-Brooke Papers, 1850/18851