- Black, Kent, and Apperson Family Papers, 1779/19841
- Blacksburg Woman's Club Records, 1907/19721
- Blanche Lemco van Ginkel Architectural Collection, 1956/20131
- Carrie T. Sibold Family Papers, 1912/1990, bulk 1974/19901
- Carter/Cash Family Collection, 1940/20091
- Civil War Small Manuscripts Collection, 1861/19961
- Claire Rufer-Eckmann Architectural Collection, 1928/19581
- College of Home Economics Metabolism Study Collection, 1956/19601
- Cynthia Addington Boatwright Papers, 1930/19901
- Dorothee Stelzer King Architectural Collection, 1950/20181
- Dorothy Alexander Architectural Collection, 1939/19941
- Dorothy H. Bodell Papers, 1850/19961
- E. Maria Roth Architectural Collection, 1940/20101
- Eleanore Pettersen Architectural Collection,, 1915/2003, bulk 1950/20001
- Elisabeth-Charlotte Harling Architectural Collection, 1950/19981