- Horatio Seymour Stahl Papers, 1881/19371
- Hotel Roanoke Architectural Drawings, 1890/19831
- J. Ambler Johnston Papers, 1901/19741
- J. Harry McBroom Papers, 1899/19081
- James H. Lane Research Collection, 1865/19911
- James I. Robertson Jr. Papers, 1849/20111
- James William McClelland V.P.I. Tableware, 1902/19041
- John A. Kircher Papers, 1889/1999, bulk 1943/19441
- John Edward Williams Papers, 1892/19401
- John M. and Cora Bolton McBryde Family Papers, 1862/20181
- John R. Hutcheson Family Collection, 1890/1969, bulk 1930/19501
- John T. Cowan Papers, 1887/19171
- Joseph F. Ware Collection, 1900/1971, bulk 1915/19201
- Larry McBryde Collection on the John McLaren McBryde Family, 1859/20131
- Lawrence Priddy Collection, 1894/19361