- Antoine Gaujot and Julien E. Gaujot Papers, 1840/19991
- Ellison A. Smyth, Jr. Papers, 1859/19271
- George W. L. Kabrich Family Papers, 1850/1947, bulk 1850/19041
- Harvey Lee Price Papers, 1853/19491
- James I. Robertson Jr. Papers, 1849/20111
- Larry McBryde Collection on the John McLaren McBryde Family, 1859/20131
- Marshall W. Fishwick Collection, 1700/2007, bulk 1923/20071
- O'Shaughnessy Family Papers, 1857/19651
- Preston and Olin Institute Records, 1852/18711
- Slusser Family Papers, 1852/19121
- Virginia Tech Corps of Cadets, Company A, Memorabilia, 1800/19701
- William Bradford Alwood Collection, 1854/19271
- William H. Ruffner Letters, 1855/18881