- Craig L. Brians Papers, 1992/20131
- Dean Carter Papers, 1950/2003, bulk 1964/19821
- Department of Biochemistry Oral History Collection, 2001/20051
- Doris Zallen Papers, 1952/20161
- Evelyn R. Klemstine Collection, 1994/20131
- Hard Times Blues Collection, 1966/20191
- Harry Downing Temple, Jr., Papers, 1872/2004, bulk 1930/20011
- Henry J. Dekker Papers, 1949/20091
- Janet Johnson Collection, 1948/20221
- Larry McBryde Collection on the John McLaren McBryde Family, 1859/20131
- Oral Histories of Technology in Teaching, 20021
- Records of HokiePRIDE, 1971/2015, bulk 1995/20131
- Records of WUVT, 1950/20081
- Records of Women and Gender in International Development, 1978/20021
- Records of the Black Student Alliance, 1993/20061