- Antoine Gaujot and Julien E. Gaujot Papers, 1840/19991
- Bertram Y. Kinzey, Jr., Papers, 1940/19551
- Beulah O. Allen Collection,, 1905/1992, bulk 1920/19701
- Blacksburg Sewage Papers, 1946/19481
- Cadet Uniform Hardware and Insignia, 1877/19521
- Carneal and Johnston Architectural Drawings, 1939/19681
- Claudius Lee Papers, 1887/19541
- Diploma Collection, 1877/19641
- Edgemont Farm Papers, 1925/19981
- Frank L. Robeson Papers, 1899/19541
- George Robert Sibold Collection, 1890/19561
- Harry Downing Temple, Jr., Papers, 1872/2004, bulk 1930/20011
- J. Ambler Johnston Papers, 1901/19741
- J. Preston Newman Papers, 1910/19751
- Jean Haskell-Speer Papers, 1782/1995, bulk 1983/19931