- Austin-Twyman Papers, 1765/19391
- Barraud Family Papers, 1799/1904, bulk 1810/18601
- Blair, Banister, Braxton, Horner, Whiting Papers, 1760/1890, bulk 1765/18171
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Campbell Family Papers, 1726/19201
- Captain James Charlton's Infantry Order Book, 1813/18151
- Caroline Baytop Sinclair Papers, 1938-1993, 1938/19931
- Christopher Tompkins Papers, 1778/18381
- Edward Coles Papers [typescripts], 1814/18571
- Flora Adams Darling papers, 1862/1908, bulk 1890/19081
- Francis Little Collection, 1770/18641
- Garth Family papers, 1798/18721
- James Jarvis Reminiscences, 18461
- James Monroe papers, 1776/1924, bulk 1783/18311
- James Patton Preston Letter, 18121