- Lawrence Washington collection of Washington family papers1
- Log Books of the Steamboat "Sonoma"1
- Lyman Stedman, Farmer and Politician, Diary1
- Maria Schwald, Diary Regarding Cruise Along the Ohio River1
- Miles Dahmer Papers1
- Nathan Hanes (1821-1899) Papers1
- Ohio River Sheet Music and Other Material1
- Ohio River Shipping Accounts1
- Pauline Morehead Ash, Collector, Papers1
- Pittenger Family Letters1
- R.H. Hendershot Shipping Bills1
- Robert E. Lee Keadle, Monroe County, Diary1
- Roy Bird Cook (1886-1961), Collector, Papers1
- Roy Bird Cook, Collector, Papers regarding the Civil War in Southern West Virginia1
- Roy Thistle, Collector, Scrapbook regarding Ohio River History1