- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/19744
- Charles E. Kilbourne personal papers, 1898/19632
- James Graham Leyburn collection, 1902/19932
- Adams T. Rice papers, 1922/19601
- Albert E. Haak Scrapbook, 1947/19771
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Alumni Association Records, 1924/20161
- American Association of University Women (AAUW) Records, Harrisonburg, Virginia Branch, 1929/20251
- Anthony-Seeger Campus School Records, 1956/19821
- Armand J. Galfo Papers, 1940/2008, bulk 1958/19951
- Arthur J. Morris memorabilia, 1884/19921
- Arthur W. and Leah James Scrapbooks, 1909/19771
- Association for the Preservation of Virginia Antiquities, Yorktown Branch Records, 1921/2013, bulk 1975/20051
- Barbara Cary Johnston Willard Scrapbook, 1800/20061
- Blackley Family papers, 1830/20201