- James Z. McChesney Papers, 1853/19591
- John R. Lynch Papers, 1856/19241
- McNeill Family Papers, 1770/19291
- Minnie Kendall Lowther Papers, 1907/19451
- Mrs. Glenn V. Longacre, Collector, Papers, 1814/19151
- Ohio Valley Floods Papers, 1913/19711
- Philip Bagdon, Research Notes regarding Cass, West Virginia, 1876/19761
- Roy Bird Cook, Collector, Papers regarding the Civil War in Southern West Virginia, 1844/1938, bulk 1861/18671
- Roy Thistle, Collector, Scrapbook regarding Ohio River History, 1855/19341
- Scott-Palmer Family Papers, 1856/19171
- Steamboats Records, 1877/19391
- Union Carbide Corporation, Hawk's Nest Project, Papers, 1873/19661
- Ward Engineering Company Archives and Manuscripts, 1871/19771
- West Virginia Pulp and Paper Company Papers, 1892/19291
- Woodbridge-Blennerhassett Papers, 1797/19351