- Harry T. Leeper, Collector, Papers, 1779/19151
- Henderson and Tomlinson Families Papers, 1789/18591
- Henry Ruffner (1790-1861) and William Henry (1824-1908) Papers, 1829/19131
- James Z. McChesney Papers, 1853/19591
- John C. Sanders, Collector, Papers, 1816/19001
- John P. Clarke (1825-1900) Papers, 1851/19001
- John R. Lynch Papers, 1856/19241
- John and Robert Thompson Diaries, 1804/18631
- McNeill Family Papers, 1770/19291
- Mrs. Glenn V. Longacre, Collector, Papers, 1814/19151
- Ohio Historical Papers, 1776/18721
- Parkersburg Town Council Journals, 1826/18741
- Robinson Family Manuscripts, 1847/18831
- Roy Bird Cook, Collector, Papers regarding the Civil War in Southern West Virginia, 1844/1938, bulk 1861/18671
- Roy Thistle, Collector, Scrapbook regarding Ohio River History, 1855/19341