- Barnhart Family Papers, 1836/19441
- Bell Hospital Records, 1926/19701
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Borland Family Papers, 1771/19401
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- Campbell Family Papers II, 1795/19451
- Catlett Family Papers, 1850/1933, bulk 1901/19291
- Civil War Collection, 1856/19381
- Daisy Bacon Papers, 1857/19861
- Diggs Family Papers, 1914/1960, bulk 1920/19401
- Earl Gregg Swem Family Papers, 1871/19841
- Earl Gregg Swem Genealogy Collection, 1719/19821
- Eldon Bowman collection of Bowman family papers, 1797/20191
- Farrar Family Papers, 1875/19641