- Lexington Presbyterian Church collection, 1824/1927, bulk 1877/19272
- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/19741
- Carlton Casey Papers, 1894/19991
- Charter Day collection, 1859/20221
- Commencement Exercises collection, 1831/20241
- Cynthia Barlowe and Raymond Kimbrough Collection, 1909/19661
- Earl Gregg Swem Family Papers, 1871/19841
- Edward R. Jones, Jr. Papers, 1861/19921
- F. H. Ball Papers, 1908/19311
- Farrar Family Papers, 1875/19641
- Frances Breeze Music Collection, 1890/19801
- Grace Warren Landrum Papers, 1890/19951
- Guy Family Papers, 1900/19881
- Heinz and Gertrud Siegel Elber papers, 1918/20181
- Helen Foss Weeks Scrapbook, 1906/19211