- A.S. Hammack papers, 1864/19541
- American Association of University Women (AAUW) Records, Harrisonburg, Virginia Branch, 1929/20251
- Blackley Family papers, 1830/20201
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- Daisy Bacon Papers, 1857/19861
- Davis, Kline, and Hutton Family papers, 1816/19771
- George E. Whitesel papers on Golden Scotch Collie breeding, 1940/19461
- Heatwole Family Papers, 1838/20011
- James Madison University memorabilia and ephemera, 1896/20141
- James Madison University vertical files, 1909/20261
- Joanne V. Gabbin Papers, 1930/2017, bulk 1960/20171
- John H. Grabill Papers, 1843/1981, bulk 1894/19221
- Julia Davis papers on The Shenandoah, 1930/19451
- Julia Smith Martin Papers, 1945/19481
- Kappa Delta Pi. Alpha Chi Chapter Records, 1923/19861