- A.S. Hammack papers, 1864/19541
- Anne Christiansen Chapman Scrapbook, 1920/19221
- Blackley Family papers, 1830/20201
- Catlett Family Papers, 1850/1933, bulk 1901/19291
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- Daisy Bacon Papers, 1857/19861
- Davis, Kline, and Hutton Family papers, 1816/19771
- Grove Family Papers, 1884/19321
- Heatwole Family Papers, 1838/20011
- James Madison University memorabilia and ephemera, 1896/20141
- James Madison University vertical files, 1909/20261
- John H. Grabill Papers, 1843/1981, bulk 1894/19221
- Nancy Bondurant Jones Papers, 1909/2011, bulk 1991/20071
- Pearl Haldeman Stickley Papers, 1910/1962, bulk 1910/19151
- Rockingham County Schools collection, 1895/19611