- Abraham Anson papers, 1939/20051
- Blackley Family papers, 1830/20201
- Blanche Lazzell, Artist, Papers, 1881/19921
- Booker T. Washington, Commemorative Articles and Other Miscellaneous Items, 1881/19811
- Charles Lietwiler transportation collection, 1903/20051
- Connie Smith family photograph album, 1950/19801
- Duncan Alexander MacLeod Collection, 1932/19861
- Earl Ray Zinn Papers, 1910/19751
- Ephemera Collection, 1900/1993, bulk 1900/19301
- Gravely and Moore Studio, Photography Business in Charleston, Negatives, 1860/1969, bulk 1930/19451
- Jacob H. Gerbrick, Photographer, Records, 1857/19741
- John Burns Murphy, Compiler, Genealogy of Murphy and Related Families, 1890/19881
- Patrick Ward Gainer (1904-1981), Collector, Papers and Folk Music Recordings, 1890/19811
- Richard McClintock Collection, 1960/20151
- Rockbridge Historical Society files on Houses, 1800/19952