- Bland Family papers, 1778/19891
- Bozarth Family Papers, 1931/1985, bulk 1931/19621
- Brian W. Blouet papers, 1942/19841
- Broome Family Papers, 1862/19951
- Bruton Parish Church (Williamsburg, Va.) records, 1662/2010, bulk 1900/20001
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- C-SPAN records, 1809/2012, bulk 1978/20121
- C. Barrett Graham papers, 1967/20161
- C. Ernest Edgar III papers, 1956/20101
- Capital Club of Williamsburg Records, 1960/2015, bulk 1970/20001
- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/19741
- Carl Van Vechten - Mark Lutz Collection, 1881/19801
- Carlton Casey Papers, 1894/19991
- Carter Lowance Papers, 1860/1993, bulk 1942/19881
- Caskie Stinnett papers, 1919/1998, bulk 1950/19931