- Alumni Association Records, 1924/20161
- American Association of University Women (AAUW) Records, Harrisonburg, Virginia Branch, 1929/20251
- Bernice Jones Smith photograph album, 1930/19391
- Betty Brown Clemmer and Willis Clemmer papers, 1920/2015, bulk 1943/19491
- Blackley Family papers, 1830/20201
- Charles Grattan Price Jr. and Don W. Thomas collection on the Chesapeake Western Railway, 1872/19961
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- Charles T. Smith photographs, 1880/2007, bulk 1990/19991
- Daisy Bacon Papers, 1857/19861
- Davis, Kline, and Hutton Family papers, 1816/19771
- Delphine Hurst Parsons papers, 1923/1976, bulk 1923/19311
- Department of Living Sciences records, 1915/20031
- Dorothy McKinley Spooner Garber Papers, 1925/19781
- Eldon Bowman collection of Bowman family papers, 1797/20191
- Ellen Stulting Wyant photograph album, 1930/19441