- CDV of Buttermilk Drinkers, 1864/18661
- Campaigns and Elections Collection, 1816/1972, bulk 19321
- Campbell Family Papers II, 1795/19451
- Campbell Family Papers, 1843/19501
- Carter Lowance Papers, 1860/1993, bulk 1942/19881
- Catlett Family Papers, 1865/19211
- Charles H. Bell Papers, 1772/1929, bulk 1852/18751
- Charles H. Dimmock Papers, 1826/18721
- Charles Mills Sheldon Papers, 1862/1928, bulk 1895/19281
- Clara L. Lawrence Papers, 1763/19391
- Commander Horace Elmer Collection, 1864/19001
- Commodore Charles H. B. Caldwell collection, 1853/18771
- Copy of a carte de visite photograph of James Edward Allan Gibbs, 1866/18701
- Craig Family Papers, 1860/1906, bulk 1860/18801
- Daingerfield Papers, 1833/19301