- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Christine Hoepfner Collection on the Shenandoah National Park, 1911/20001
- Cynthia Barlowe Collection, 1902/20011
- Davidson Family Papers, 1773/19381
- Eldon Bowman collection of Bowman family papers, 1797/20191
- Flinn Family papers, 1899/20201
- Genealogy Collection, 1880/20011
- George Washington Papers [in part: photostats, printed copies, typescripts], 1755/19321
- Gordon W. Miller Collection on Gabriel Thomas Barbee, 1787/20051
- Hickory Neck Church records, 1721/20241
- Jay W. Johns, Jr. Papers, 1918/19791
- John Allan Family Papers, 1795/19861
- Patricia Turner Ritchie collection on Brocks Gap, 1750/19901
- Pulaski Club Records, 1877/20141
- Thelma Pedersen Collection, 1899/19881