- Arithmetic Notebook, I, 1780/18201
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bishop James Madison's preparatory notes on Smith's Wealth of Nations, 1776/18121
- Charles H. Bell Papers, 1772/1929, bulk 1852/18751
- Fairfax Harrison Papers, 1736/19451
- Henkel Family Papers, 1783/18741
- J.T. McAllister's Notebooks on the Revolutionary War and Virginia Counties, 1780/19121
- James Lewis Notebook, 1779/18441
- James M. Owens Collection of Madison Family Material, 1776/19531
- John Page Memorandum Book, 1762/17971
- John Sublet Arithmetic Book, 1766, 1816, 1766/18161
- John Womack Wright Collection of Maps, 1675/19181
- Marie M. and Edith W. Smith Papers, 1783/18621
- Mary and Hannah Gibbons Papers, 1743/18901
- Moncure Robinson Papers, 1787/18891