- Alexander Haight family collection, 1764/19761
- C-SPAN records, 1809/2012, bulk 1978/20121
- C. Harrison Mann, Jr. papers, 1832/19791
- Campbell Family Papers, 1843/19501
- Chester McNerney Collection, 1290/19501
- Ephemera Collection, 1800/20141
- Gregory Family papers, 1829/1920, bulk 1880/19001
- Harrison Holt Riddleberger Papers, 1872/19021
- Henkel Family Papers, 1783/19101
- James Madison Memorabilia, 1796/19511
- John Alexander Graham Papers, 1910/1947, bulk 1915/19471
- John Tyler, Jr. Papers, 1800/19281
- Lee Family Papers, 1858/1976, bulk 1900/19501
- Matthew Whaley School Collection, 1850/2012, bulk 1880/19601
- Merkling Historic Events Newspaper Collection, 1891/19681