- Roy Rosenzweig papers, 1934/20071
- Saint Andrew's Society of Washington, D.C. records, 1861/19951
- School of Education Records, 1930/20081
- Science Fiction and Fantasy Club Records, 1975/2002, bulk 1990/20021
- Sexual Orientation, Gender Identity and Expression (SOGIE) Programming Records, 1984/20241
- Shenandoah Valley Bicycle Coalition Records, 1977/20191
- Sigma Alpha Epsilon records, 1924/20041
- Sixty-Seventh Field Hospital Collection, 1943/2002, bulk 1943/20021
- Strother Family Papers, 1993/19941
- Summer Session Records, 1912-2000, 1912/20001
- Taylor Family Papers, 1903/19571
- Thomas E. Pugh Papers, 1914/2001, bulk 1941/19981
- U.S.S. Attala Papers, 1945/19461
- Valley of Virginia Pen Women Records, 1950/20131
- Vincent T. DeVita, Jr. Papers, 1964/19881