- Anna Burton Ellett Collection, 1751/19321
- Association for the Preservation of Virginia Antiquities, Montgomery County Branch Papers, 1754/1996, bulk 1958/19831
- Bell, Kent, Cloyd, Withrow Family Collection, 1780/19981
- Bigler-Sessler-John Family Papers, 1752/19251
- Black, Kent, and Apperson Family Papers, 1779/19841
- Blacksburg [Virginia] Presbyterian Church Land Deeds, 1850/19241
- Brown Family Papers, 1825/1965, bulk 1850/18941
- Charles A. Miller Family Papers, 1708/19261
- Charles W. Crush Collection, 1796/19781
- Charlton Family Papers, 1853/19581
- Christiansburg Presbyterian Church Minute Book, 1869/18971
- Christiansburg [Virginia] Industrial Institute Historical Documents, 1866/19911
- Civil War Small Manuscripts Collection, 1861/19961
- Croy Family Papers, 1859/19381
- Dorothy H. Bodell Papers, 1850/19961