- Black, Kent, and Apperson Family Papers, 1779/19841
- Brown Family Papers, 1825/1965, bulk 1850/18941
- Daniel E. Wright Papers, 1903/19731
- Dickinson Family Papers, 1871/19311
- Dillon Family Papers, 1805/19441
- Elden E. Billings Collection, 1862/19911
- Guy Di Carlo, Jr., Civil War Research Papers, 1862/20021
- Isaac White Letters, 1861/19381
- James Tarter Ledgers, 1879/19411
- John Harville Diaries, 1861/2010, bulk 1861/18641
- Linwood D. Keyser Papers, 1889/19441
- Maupin-Washington Papers, 1732/19321
- Squire Bosworth, Physician, Papers, 1786/19641
- West Virginia University, Medical Education History, Research Notes, 1869/19641