- Black, Kent, and Apperson Family Papers, 1779/19841
- Brown Family Papers, 1825/1965, bulk 1850/18941
- Dillon Family Papers, 1805/19441
- Elden E. Billings Collection, 1862/19911
- Guy Di Carlo, Jr., Civil War Research Papers, 1862/20021
- Isaac White Letters, 1861/19381
- James R. Perdue Family Collection, 1868/19191
- John Harville Diaries, 1861/2010, bulk 1861/18641
- Maupin-Washington Papers, 1732/19321
- Meade & Baker Apothecary Ledger, 1861/18701
- Medical Bill Signed by Dr. Harvey Black, 1865/18791
- Robert Ellett Account Book, 1867/18731
- Robinson Family Manuscripts, 1847/18831
- Salt Sulphur Springs Records, 1825/18831
- Squire Bosworth, Physician, Papers, 1786/19641