- A Topographical Map of the Guy's Run Iron Lands, Rockbridge Co., Va. (reproduction), 18781
- A. J. Davis Family Collection, 1874/2007, bulk 1874/19071
- Alexander Farish Robertson Papers, 1867/19311
- Alexander McNutt Glasgow Family Papers, 1823/19031
- Anna Burton Ellett Collection, 1751/19321
- Association for the Preservation of Virginia Antiquities, Montgomery County Branch Papers, 1754/1996, bulk 1958/19831
- Augustus Smith Family Collection, 1864/19261
- Baldwin Family Letters, 1861/18971
- Barclay Shipping Ledger, 1847/18781
- Bear Family Papers, 1823/18791
- Bell, Kent, Cloyd, Withrow Family Collection, 1780/19981
- Benjamin Huddle Diary, 1861/20061
- Bigler-Sessler-John Family Papers, 1752/19251
- Black, Kent, and Apperson Family Papers, 1779/19841
- Blacksburg [Virginia] Presbyterian Church Land Deeds, 1850/19241