- Hunt Family Papers, 1760/19461
- Ingles Family Collection, 1797/18231
- J. Hoge Tyler Family Collection, 1802/19561
- J. M. Tise Ledger and Tise Family Receipts, 1798/19371
- Jamerson-Webster-Basham Family Papers, 1792/19361
- James Murphy Inventory of Estate, 18121
- Jean Haskell-Speer Papers, 1782/1995, bulk 1983/19931
- John Janney Papers, 1811/1994, bulk 1840/18801
- John Nicolay Papers, 1782/19831
- John Preston Letter to W. Ready, 18121
- John Preston Papers, 1796/18441
- Kincaid Family Papers, 1803/18801
- Landon Duncan Letters, 1812/18371
- Michael Kinzer Family Papers, 1805/19811
- Nelson Family Papers, 1783/18721