- Carol Barton papers, 1973/20201
- Carrie Bishop Scrapbook, 1914/19181
- Catlett Family Papers, 1850/1933, bulk 1901/19291
- Catlett Family Papers, 1865/19211
- Chandi J. Singer papers, 1966/20221
- Charles Carter Letter to Edmund Pendleton, 17831
- Charles Grattan Price Jr. and Don W. Thomas collection on the Chesapeake Western Railway, 1872/19961
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- Charles Jackson Letter Books, 1890/19041
- Charles P. Shepard Letter, 18621
- Charles Spitzer Letters, 1833/18861
- Charles Triplett O'Ferrall papers, 1870/18931
- Charles and William Person Papers, 1900/2011, bulk 1920/19501
- Chesapeake Western Railway Company Records, 1916/19821
- Christine Hoepfner Collection on the Shenandoah National Park, 1911/20001