- Allen-Kean-Laurence family letters, 1837/19601
- Barnhart Family Papers, 1836/19441
- Blackley Family papers, 1830/20201
- Booton-Modesitt Family Papers, 1809/1880, bulk 1820/18501
- Brown Family Papers, 1836/19081
- Charles Spitzer Letters, 1833/18861
- Clara L. Lawrence Papers, 1763/19391
- Collection of French Language Manuscripts, 1633/1942, bulk 1633/19421
- Davis, Kline, and Hutton Family papers, 1816/19771
- Eldon Bowman collection of Bowman family papers, 1797/20191
- Geddy-Harris Archive Records, 1773/1959, bulk 1890/19401
- George Michener Hart Collection on Moncure Robinson, 1816/19191
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Harrisonburg-Rockingham Historical Society Collection, 1740/19501
- Henkel Family Papers, 1801/20081