- Booton-Modesitt Family Papers, 1809/1880, bulk 1820/18501
- Clara L. Lawrence Papers, 1763/19391
- Collection of French Language Manuscripts, 1633/1942, bulk 1633/19421
- Eldon Bowman collection of Bowman family papers, 1797/20191
- Geddy-Harris Archive Records, 1773/1959, bulk 1890/19401
- Gregory Page Letter to "Mama", 18121
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Harrisonburg-Rockingham Historical Society Collection, 1740/19501
- Henkel Family Papers, 1801/20081
- James Madison Memorabilia, 1796/19511
- John Randolph The Tory Papers, 1779/1840, bulk 1779/18401
- John T. Harris papers, 1771/1937, bulk 1850/19001
- Liskey Collection of Heavner Family Papers, 1788/19671
- Manley Family papers, 1707/19531
- Margaret B. Burruss Collection of Scott and Saufley Family Papers, 1786/19121