- Harrisonburg-Rockingham Historical Society Collection, 1740/19501
- Leslie Cheek, Jr. Papers, 1930/1957, bulk 1940/19551
- Manley Family papers, 1707/19531
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Mary A. Thompson Papers, 1893/19741
- Maury Family papers, 1777/19771
- Mills E. Godwin, Jr. Papers, 1712/1989, bulk 1947/19891
- Minor Wine Thomas, Sr. Papers, 1920/19521
- Mr. and Mrs. James Hoover Collection of Strickler Family Papers, 1770/19631
- Office of the President: G. Tyler Miller Papers, 1941/19981
- Overton family papers, 1727/1961, bulk 1781/18751
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/19741
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- Richard Lee Morton papers, 1756/2006, bulk 1930/19691
- Roane Family Papers, 1880/1973, bulk 19501