- Legal Documents, 1742/18953
- Adams Papers, 1782/18901
- Alexander M. Davis Papers, 1850/18921
- Anderson Family papers, 1755/19581
- Austin-Twyman Papers, 1765/19391
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Benjamin Thompson Papers, 1810/18961
- Bland Family papers, 1778/19891
- Brafferton Estate Collection, 1691/19351
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Bucktrout-Braithwaite Papers, 1780/1996, bulk 1890/18991
- C. L. Worthington Papers, 1752/19381
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Calfee Family Papers, 1812/1919, bulk 1859/18891