- Booton-Modesitt Family Papers, 1809/1880, bulk 1820/18501
- Cabaniss Family Papers, 1800/18371
- Campbell Family Papers, 1726/19201
- Charles Brown Papers, 1792/18881
- Dromgoole Family Papers, 1821/1896, bulk 1850/18901
- Francis Scott Key Papers, 1779/18421
- Henkel Family Papers, 1783/18741
- John "Jack" Fitzgerald Papers, 1827/18551
- John B. Colin Papers, 1816/18521
- McGavock Family Papers, 1760/18881
- Medical Accounts of Drs. Peter Ludlow and Alexander Somervail, 1811/18341
- Nineteenth Century Invoices and Receipts Collection, 1804/18891
- Peter Goelet Papers, 1762/1886, bulk 1770/17791
- Richard Blow Papers, 1772/18721
- Robert Barraud Taylor Invoice and Receipt Book, 1825/18311