- Baer Family Papers, 1744/19291
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bowman Family Papers, 1765/19981
- Chester McNerney Collection, 1290/19501
- Davis, Kline, and Hutton Family papers, 1816/19771
- Eldon Bowman collection of Bowman family papers, 1797/20191
- George Washington collection, 1775/19491
- John T. Harris papers, 1771/1937, bulk 1850/19001
- Manley Family papers, 1707/19531
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19101
- McCown Family Papers, 1811/19171
- Richard G. Joynt Collection of British Manuscripts, 1593/20151
- Rockbridge Historical Society collection of deeds, 1748/19201
- The Reverend Henry Gardiner Lane Memorial Collection, 1799/19381
- Tisinger Family collection of Shenandoah County land surveys, 1749/19321