- Thomas Ray Dille Papers, 1774/19392
- Adams Papers, 1782/18901
- Alexander Brown Papers (II), 1748/19001
- Alexander Lockhart Nelson papers, 1848/19021
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651
- Andrew Nelson Campbell, Civil War Veteran and Monroe County Politician, Papers, 1856/19321
- Anita Cutright Burnett, Collector, Papers, 1790/19351
- Aretas Brooks Fleming (1839-1923) Papers, 1784/19241
- Aretas Brooks Fleming Papers, 1784/19241
- Armistead Boothe Papers (MS164), 1803/19901
- Baer Family Papers, 1744/19291
- Barbara Cary Johnston Willard Scrapbook, 1800/20061
- Beall, Henry, & McClure Families Papers, 1800/19681
- Benjamin Stoddert Ewell Papers, 1784/1934, bulk 1830/18921
- Bevill Family Papers, 1558/1939, bulk 1558/17071