- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/19791
- Anne H. Cutler Papers, 1930/2013, bulk 1954/20001
- Association for the Preservation of Virginia Antiquities, Colonial Capitol Branch Records, 1896/19891
- Bell Hospital Records, 1926/19701
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Bozarth Family Papers, 1931/1985, bulk 1931/19621
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Campbell Family Papers II, 1795/19451
- Charles J. Duke, Jr. Papers, 1919/19581
- College Papers Collection, 1880/19991
- College Women's Club Records, 1944/19921
- College of William and Mary Audit Reports Collection, 1934/19881
- Dora and Cara Armistead Papers, 1880/19501
- Earl Gregg Swem Family Papers, 1871/19841