- Earl Gregg Swem Genealogy Collection, 1719/19821
- Fairfax Harrison Papers, 1736/19451
- Francis Little Collection, 1770/18641
- Galt Papers (I), 1745/18921
- Galt Papers (III), 1750/19911
- George Mason Papers, 1706/18581
- George Washington collection, 1654/17992
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Jerdone Family papers, 1753/18901
- John Dandridge Papers, 1767/18251
- John Dixon Papers, 1729/18291
- John Garland Pollard Papers, 1683/1968, bulk 1856/19371
- John Murray, 4th Earl of Dunmore Papers, 1768/18041
- Leven Powell papers, 1774/18061
- Lexington Arsenal and Virginia Militia records, 1702/18392